A couple of critiques of Behe’s book:
Behe doubles down on his claim that the evolution of chloroquine resistance in malaria by random mutations is exceedingly unlikely because at least two mutations are required, neither of which is beneficial without the other. His calculations have already been refuted (5), and it has long been known that neutral and even deleterious mutations can provide stepping stones to future adaptations. Indeed, a 2014 study, unmentioned by Behe, reported discovery of two genetic paths through which malaria has evolved chloroquine resistance through multiple steps (6)
The whole point is that everyone accepts that raw combinatorial processes - random chemistry - can't be the explanation, so natural selection is invoked instead. However then we see examples like this where two things have to develop with no help from NS because neither is beneficial on their own, but then they combine - only that last step is actually beneficial.
Suppose we imagine that Yaweh did it all, just as it says in the Old Testament (just for argument, you understand) and somehow we could travel back in time and observe the process biochemically. What would we see? Well various genes would appear, and serve no obvious purpose, and then two or more of them would combine together to do something useful! At that scale it might look very like what was being discussed above, but obviously NS couldn't be the explanation!